Clinical Definition

Hodgkin disease, or Hodgkin’s disease, is a malignant neoplasm of lymphoid cells and is one type of lymphoma. It differs from other lymphomas in that it produces abnormal Reed-Sternberg cells. It is characterized by enlargement of the lymph nodes, spleen and possibly liver.

Hodgkin disease is divided into two main subtypes based on histopathologic criteria. It often has a good prognosis if treated early enough.

In Our Own Words

Considered one of the most curable forms of cancer, Hodgkin disease is a cancer that develops in the lymphatic system. The lymphatic system is part of the body’s immune system and helps fight infection.

Hodgkin disease is a type of lymphoma. In fact, lymphomas are classified broadly as Hodgkin or non-Hodgkin; people with Hodgkin disease produce a specific type of cell called a Reed-Sternberg cell.