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Sickle Cell Disease

Clinical Definition Sickle cell disease is a group of hereditary disorders of erythrocytes, typically diagnosed in neonates with a blood test. Homozygous and compound heterozygous individuals have symptomatic disease, while heterozygous individuals have sickle cell trait, a generally benign condition. SCD is characterized by anemia, pain, potentially life-threatening complications such as bacterial septicemia, acute chest

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